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NOTE: The Solicitations and topics listed on this site are copies from the various SBIR agency solicitations and are not necessarily the latest and most up-to-date. For this reason, you should visit the respective agency SBIR sites to read the official version of the solicitations and download the appropriate forms and rules.
If no search results for your keyword(s) were found, you are encouraged to review Agency omnibus solicitations for additional funding opportunities. Omnibus solicitations are structured to be broad, extensive Programmatic issuances with research areas related to the petitioning Agency and are not limited to predetermined Topics/Subtopics. If upon reviewing you have additional questions, you may consider reaching out to the respective Agency for clarification regarding acceptable proposals (https://www.sbir.gov/agency-contacts).
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PAR-20-111: Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
Release Date: 03-02-2020Open Date: 07-11-2020 Due Dates: Multiple Close Date: 05-08-2023A. Overview Recent advances in neuroscience offer unprecedented opportunities to discover new treatments for nervous system disorders. However, before a new chemical entity can be tested in a clinical setting, it must undergo a process of chemical optimization to improve potency, selectivity, and drug-like properties, followed by pre-clinical safety testing to meet the standards set by the Food a ...
SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
PAR-21-247: Technology Development for Single-Molecule Protein Sequencing (R43/R44 Clinical Trial Not Allowed)
Release Date: 07-09-2021Open Date: 10-01-2021 Due Dates: Multiple Close Date: 06-16-2023Purpose This Funding Opportunity Announcement (FOA) solicits R43/R44 grant applications to accelerate innovation and early development in the emerging field of single-molecule protein sequencing (SMPS). This FOA is seeking novel technologies or significant improvements to existing technologies. Exploration of technologies other than those currently being commercialized is highly encouraged. The s ...
SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
PAR-21-059: linical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)
Release Date: 11-19-2020Open Date: 01-22-2021 Due Dates: Multiple Close Date: 09-08-2023Background A biomarker is a defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities are diverse, and can include ‘omics, imaging, behavioral, digital and physiologic endpoints, as well as composite biomarkers or biomarker signatures. Bioma ...
SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
PAR-21-057: Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U44 Clinical Trial Optional)
Release Date: 11-19-2020Open Date: 01-22-2021 Due Dates: Multiple Close Date: 09-08-2023Background A biomarker is a defined characteristic that is measured as an indicator of normal biological processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities are diverse, and can include ‘omics, imaging, behavioral, digital and physiologic endpoints, as well as composite biomarkers or biomarker signatures. Becaus ...
SBIRPhase I/Phase IIDepartment of Health and Human ServicesNational Institutes of Health -
C41-04: RF GUN AND VACUUM TECHNOLOGIES FOR LIGHT SOURCE FACILITIES
Release Date: 10-18-2021Open Date: 10-18-2021Due Date: 12-01-2023Close Date: 12-01-2023Robust Microwave Thermionic Electron Gun C41-04 FY 2022 SBIR/STTR Phase II Release 1 Department of Energy ...
SBIR/STTRPhase I/Phase IIDepartment of Energy -
C41-08: INSTRUMENTATION FOR ADVANCED CHEMICAL IMAGING
Release Date: 10-18-2021Open Date: 10-18-2021Due Date: 12-01-2023Close Date: 12-01-2023Time-Resolved Chemical Information from Hybrid Probe Microscopies C41-08 FY 2022 SBIR/STTR Phase II Release 1 Department of Energy ...
SBIR/STTRPhase I/Phase IIDepartment of Energy -
C43-10: HIGH PERFORMANCE MATERIALS FOR NUCLEAR APPLICATION
Release Date: 10-18-2021Open Date: 10-18-2021Due Date: 12-01-2023Close Date: 12-01-2023In Situ Mitigation and Repair of Materials Degradation C43-10 FY 2022 SBIR/STTR Phase II Release 1 Department of Energy ...
SBIR/STTRPhase I/Phase IIDepartment of Energy -
C43-15: MEMBRANES AND MATERIALS FOR ENERGY EFFICIENCY
Release Date: 10-18-2021Open Date: 10-18-2021Due Date: 12-01-2023Close Date: 12-01-2023Innovative Approaches Toward Discovery and Development of Novel, Durable Supports for Low-Platinum Group Metal (PGM) Catalysts for Polymer Electrolyte Membrane Fuel Cells C43-15 FY 2022 SBIR/STTR Phase II Release 1 Department of Energy ...
SBIR/STTRPhase I/Phase IIDepartment of Energy -
C43-17: ADVANCED FOSSIL ENERGY TECHNOLOGY RESEARCH
Release Date: 10-18-2021Open Date: 10-18-2021Due Date: 12-01-2023Close Date: 12-01-2023Shale Gas Conversion to Liquid Fuels and Chemicals CO2 Capture – Enabling Advanced Process Systems C43-17 FY 2022 SBIR/STTR Phase II Release 1 Department of Energy ...
SBIR/STTRPhase I/Phase IIDepartment of Energy -
C43-19: TECHNOLOGIES FOR CHARACTERIZING AND MONITORING COMPLEX SUBSURFACE SYSTEMS
Release Date: 10-18-2021Open Date: 10-18-2021Due Date: 12-01-2023Close Date: 12-01-2023Real-Time, In Situ Measurements of Hydrobiogeochemical and Microbial Processes in Complex Subsurface Systems C43-19 FY 2022 SBIR/STTR Phase II Release 1 Department of Energy ...
SBIR/STTRPhase I/Phase IIDepartment of Energy
